Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604452 | 0.91 | CETP (0.37) | CETPLMNAKMT2AMEN1GAA | |
| SCHEMBL7610496 | 0.77 | CETP (0.35) | CETPLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL7605209 | 0.77 | PTGS1 (0.36) | CETPKMT2AMEN1TSHRALOX15 | |
| SCHEMBL7609236 | 0.75 | CETP (0.36) | CETPTSHRFOLH1 | |
| SCHEMBL7650534 | 0.75 | ELANE (0.40) | CETPLMNAHTTRAB9AELANE | |
| SCHEMBL7609331 | 0.74 | AKR1B1 (0.39) | CETPKMT2ATSHRALOX15 | |
| SCHEMBL8061143 | 0.68 | CETP (0.36) | CETPLMNARAB9AKMT2AALDH1A1 | |
| SCHEMBL19094074 | 0.67 | CETP (0.41) | CETPHTTKMT2AALDH1A1MEN1 | |
| Propionic Acid SCHEMBL28574297 | 0.67 | CETP (0.62) | CETPRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL29220005 | 0.66 | ACHE (0.45) | LMNAHTTELANEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |