Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125008 | 0.96 | SMN1; SMN2 (0.65) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 | |
| SCHEMBL14274943 | 0.86 | MEN1 (0.55) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 | |
| SCHEMBL9064816 | 0.83 | ADORA2A (0.67) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 | |
| SCHEMBL28088255 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 | |
| Benzoguanamine SCHEMBL917182 | 0.80 | ADORA2A (1.00) | TSHRNPSR1ADORA2AADORA1ADORA3 | |
| SCHEMBL3424387 | 0.80 | ADORA2A (0.90) | TSHRNPSR1ADORA2AADORA1ADORA3 | |
| Benzoguanamine SCHEMBL27898 | 0.80 | ADORA2A (1.00) | TSHRNPSR1ADORA2AADORA1ADORA3 | |
| Benzoguanamine SCHEMBL28634836 | 0.80 | ADORA2A (1.00) | TSHRNPSR1ADORA2AADORA1ADORA3 | |
| SCHEMBL26793554 | 0.79 | L3MBTL1 (0.67) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 | |
| Aniline SCHEMBL28092796 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRNPSR1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033093-B | N- substituted sulphonamide compound and the preparation method and application thereof | 浙江工业大学 | 2019-09-03 | — | — | CN | claimed |
| CN-108794414-B | Aromatic amido substituted s-triazine compound, preparation and application thereof | 浙江大学 | 2021-01-01 | — | — | CN | disclosed |
| CN-107286109-B | Aryl substituted sulfonamide compound and preparation method and application thereof | 浙江工业大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-107033093-B | N- substituted sulphonamide compound and the preparation method and application thereof | 浙江工业大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-107033093-B | N- substituted sulphonamide compound and the preparation method and application thereof | 浙江工业大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-105837525-B | 2, 4-diamine-1, 3,5-triazine compound and preparation method and application thereof | 浙江工业大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-108794414-A | The s-triazine compound of aromatic amide substitution and preparation and application | 浙江大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-105732528-B | Preparation method of 2-arylamine-4-dimethylamine-1, 3, 5-triazine compound | 浙江工业大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-107033093-A | N substituted sulphonamide compounds and preparation method and application | 浙江工业大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-105837525-A | 2, 4-diamine-1, 3, 5-triazine compound and preparation method and application thereof | 浙江工业大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105732528-A | Preparation method of 2-arylamine-4-dimethylamine-1, 3, 5-triazine compound | 浙江工业大学 | 2016-07-06 | — | — | CN | disclosed |
| US-6441174-B1 | REACTING PERYLENE-3,4,9,10-TETRACARBOXIMIDE OR DERIVATIVES WITH FORMALDEHYDE TO FORM BIS(HYDROXYMETHYL)PERYLENE-3,4,9,10-TETRACARBOXIMIDE, WHICH FURTHER REACTS WITH A PRECURSOR OF ORGANIC REDICALS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-08-27 | — | — | US | disclosed |
| US-20020052500-A1 | Process for preparing bis(hydroxymethyl)perylenetetracarboximide | HENDI SHIVAKUMAR BASALINGAPPA (US) | 2002-05-02 | — | — | US | disclosed |
| US-6348595-B1 | PERYLENE-3,4,9,10-TETRACARBOXIMIDE IS HYDROXYMETHYLATED BY REACTION WITH FORMALDEHYDE TO FORM BIS(HYDROXYMETHYL) PERYLENE-3,4,9,10-TETRACARBOXIMIDE; ONE POT PROCESS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052500-A1 | Process for preparing bis(hydroxymethyl)perylenetetracarboximide | TET1, CYP2E1, TET3 | SMN1; SMN2 2969/4885TSHR 4258/4885NPSR1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.