Chloromethane

Chloromethane

SCHEMBL7608703

CC1(C)C2=Cc3ccccc3C2[Zr]C2C1=Cc1ccccc12.CCl

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200812 0.96 HTR2A (0.32) HTR2A
SCHEMBL4443650 0.73 HTR2A (0.31) HTR2A
SCHEMBL5666380 0.70
SCHEMBL8024357 0.69 DRD2 (0.35)
SCHEMBL12814938 0.69 DRD2 (0.35)
SCHEMBL7602772 0.69 HTR2A (0.31) HTR2A
Hydrochloric Acid SCHEMBL4078684 0.69 HTR2A (0.31) HTR2A
SCHEMBL7196912 0.69 HTR2A (0.31) HTR2A
Hydrochloric Acid SCHEMBL547310 0.69 HTR2A (0.31) HTR2A
SCHEMBL7599525 0.69 HTR2A (0.31) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979232-B1 PROCESS FOR THE PREPARATION OF METALLOCENE COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2002-10-09 EP disclosed
US-6191294-B1 SIMPLE, HIGH-SPEED, ONE-STEP PREPARATION OF CATALYSTS FOR THE ADDITION POLYMERIZATION, OLIGOMERIZATION, HYDROGENATION OF OLEFINS; REACTING A MONOANIONIC SIGMA LIGAND, A GROUP 1A OR 2A METAL COMPOUND AND A TRANSITION METAL COMPOUND MONTELL TECHNOLOGY COMPANY BV (NE) 2001-02-20 US disclosed