Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929995 | 0.96 | BRD4 (0.35) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| SCHEMBL1922929 | 0.96 | BRD4 (0.35) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6064765 | 0.95 | BRD4 (0.34) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7642995 | 0.95 | BRD4 (0.34) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| SCHEMBL8071475 | 0.95 | BRD4 (0.34) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Phenol SCHEMBL23273222 | 0.88 | CA12 (0.35) | BRD4CCL2HTR6HTR2ATDP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7681346 | 0.85 | BRD4 (0.31) | BRD4CCL2 | |
| SCHEMBL8596413 | 0.83 | POLB (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL8380981 | 0.82 | POLB (0.33) | MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL5174476 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTGAATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979232-B1 | PROCESS FOR THE PREPARATION OF METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6191294-B1 | SIMPLE, HIGH-SPEED, ONE-STEP PREPARATION OF CATALYSTS FOR THE ADDITION POLYMERIZATION, OLIGOMERIZATION, HYDROGENATION OF OLEFINS; REACTING A MONOANIONIC SIGMA LIGAND, A GROUP 1A OR 2A METAL COMPOUND AND A TRANSITION METAL COMPOUND | MONTELL TECHNOLOGY COMPANY BV (NE) | 2001-02-20 | — | — | US | disclosed |