Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | TPH1 | P17752 | 5/20 | 0.48 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608759 | 1.00 | SLC7A5 (0.57) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL7310205 | 0.98 | SLC7A5 (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL7310195 | 0.98 | SLC7A5 (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL837014 | 0.80 | SLC7A5 (0.74) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL156189 | 0.80 | SLC7A5 (0.74) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL414363 | 0.79 | SLC7A5 (0.78) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL93494 | 0.79 | SLC7A5 (0.78) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL93495 | 0.79 | SLC7A5 (0.78) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL180272 | 0.79 | SLC7A5 (0.78) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1796036 | 0.79 | SLC7A5 (0.78) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448408-B1 | CHEMICAL INTERMEDIATES IN PREPARATION OF N-MERCAPTOACYL DERIVATIVE OF PHENYLALANINE WITH PHARMALOGICAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2002-09-10 | — | — | US | disclosed |
| US-20020028946-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.P.A. (IT) | 2002-03-07 | — | — | US | disclosed |
| EP-0948492-B1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON SPA (IT) | 2001-07-11 | — | — | EP | disclosed |
| EP-0948492-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.p.A. (IT) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028284-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.P.A. (IT) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028946-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | PAH, TYR, CYP2S1 | SLC7A5 51/4885PTGS1 1682/4885ALPI 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.