Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268393 | 0.98 | CYP4F2 (0.56) | CYP4F2CYP4A11PPARAPPARGHDAC1 | |
| SCHEMBL4268403 | 0.94 | CYP3A4 (0.53) | CYP4F2CYP4A11PPARAPPARGHDAC1 | |
| SCHEMBL14445676 | 0.88 | PPARA (0.66) | PPARAPPARGHDAC1HDAC6 | |
| SCHEMBL1517301 | 0.88 | PPARA (0.66) | PPARAPPARGHDAC1HDAC6 | |
| SCHEMBL1561685 | 0.87 | CYP3A4 (0.56) | CYP4F2CYP4A11CYP3A4LMNAMTNR1A | |
| SCHEMBL27865972 | 0.86 | PPARA (0.63) | PPARAPPARGCYP3A4LMNAMTNR1A | |
| SCHEMBL30631323 | 0.86 | PPARA (0.63) | PPARAPPARGCYP3A4LMNAMTNR1A | |
| SCHEMBL30375077 | 0.85 | PPARA (0.62) | PPARAPPARGCYP3A4LMNA | |
| SCHEMBL4279635 | 0.85 | CYP3A4 (0.50) | PPARAPPARGHDAC1HDAC6CYP3A4 | |
| SCHEMBL5280181 | 0.85 | CYP3A4 (0.50) | CYP4F2CYP4A11PPARAPPARGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451957-B1 | (Hydroxyalkyl)phenols, method for their preparation, and uses thereof | GENERAL ELECTRIC COMPANY | 2002-09-17 | — | — | US | disclosed |
| WO-2001046103-A1 | (HYDROXYALKYL)PHENOLS, METHOD FOR THEIR PREPARATION, AND USES THEREOF | GENERAL ELECTRIC COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |