Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608981 | 1.00 | ACACB (0.58) | ACACBPDE4BSIGMAR1 | |
| SCHEMBL11235329 | 0.92 | ACACB (0.60) | ACACBSIGMAR1 | |
| SCHEMBL11235575 | 0.84 | ACACB (0.58) | ACACB | |
| SCHEMBL7610862 | 0.83 | ACACB (0.57) | ACACB | |
| SCHEMBL7610856 | 0.83 | ACACB (0.57) | ACACB | |
| SCHEMBL11480710 | 0.82 | ACACB (0.62) | ACACB | |
| SCHEMBL9684956 | 0.81 | ACACB (0.52) | ACACB | |
| SCHEMBL9684948 | 0.81 | ACACB (0.52) | ACACB | |
| SCHEMBL9684941 | 0.81 | ACACB (0.52) | ACACB | |
| SCHEMBL825426 | 0.81 | ACACB (0.83) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820984-B1 | Activated amphetamines | ROCHE DIAGNOSTICS GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-5976812-A | Activated amphetamines | ROCHE DIAGNOSTICS GMBH (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0820984-A1 | Activated amphetamines | Roche Diagnostics GmbH (DE) | 1998-01-28 | — | — | EP | disclosed |