Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684956 | 1.00 | ACACB (0.52) | ACACBTBXAS1 | |
| SCHEMBL9684948 | 1.00 | ACACB (0.52) | ACACBTBXAS1 | |
| Bicarbonate SCHEMBL11017856 | 0.86 | ACACB (0.53) | ACACB | |
| SCHEMBL10633532 | 0.86 | ACACB (0.54) | ACACB | |
| SCHEMBL7608980 | 0.81 | ACACB (0.58) | ACACB | |
| SCHEMBL7608981 | 0.81 | ACACB (0.58) | ACACB | |
| SCHEMBL7610856 | 0.80 | ACACB (0.57) | ACACB | |
| SCHEMBL7610862 | 0.80 | ACACB (0.57) | ACACB | |
| SCHEMBL11235575 | 0.79 | ACACB (0.58) | ACACB | |
| SCHEMBL11235329 | 0.78 | ACACB (0.60) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0140243-A2 | Phenoxypropanol amines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-08 | — | — | EP | disclosed |