Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7621062 | 0.99 | SLC6A2 (0.65) | SLC6A2MAPTMKNK1MKNK2TGFBR1 | |
| SCHEMBL7610925 | 0.84 | SLC6A2 (0.65) | SLC6A2MAPTMKNK1MKNK2TGFBR1 | |
| Hydrochloric Acid SCHEMBL7617563 | 0.83 | SLC6A2 (0.64) | SLC6A2MAPTMKNK1MKNK2TGFBR1 | |
| SCHEMBL8946156 | 0.82 | SLC6A2 (0.49) | SLC6A2MAPTMKNK1MKNK2BCHE | |
| SCHEMBL7611649 | 0.82 | SLC6A2 (0.65) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL3977692 | 0.81 | SLC6A2 (0.64) | SLC6A2BCHE | |
| SCHEMBL9795990 | 0.80 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL7611577 | 0.78 | SLC6A2 (0.49) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL7613979 | 0.77 | SLC6A2 (0.48) | SLC6A2BCHE | |
| SCHEMBL9796088 | 0.76 | SLC6A2 (0.44) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | claimed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | claimed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | disclosed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | disclosed |
| US-5039811-A | Analgesics, antidepressants, memory activators; condensation, reduction | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4970218-A | ANALGESIC, ANTIDEPRESSANT, MEMORY ENHANCEMENT | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-11-13 | — | — | US | disclosed |