Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611649 | 0.88 | SLC6A2 (0.65) | SLC6A2BCHE | |
| Hydrochloric Acid SCHEMBL3977692 | 0.87 | SLC6A2 (0.64) | SLC6A2BCHE | |
| SCHEMBL8946101 | 0.84 | BCHE (0.42) | SLC6A2BCHEMAPT | |
| SCHEMBL7610925 | 0.83 | SLC6A2 (0.65) | SLC6A2BCHEMAPTMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL7617563 | 0.82 | SLC6A2 (0.64) | SLC6A2MAPTMKNK1MKNK2 | |
| SCHEMBL7609158 | 0.82 | SLC6A2 (0.66) | SLC6A2BCHEMAPTMKNK1MKNK2 | |
| SCHEMBL8946215 | 0.81 | SLC6A2 (0.56) | SLC6A2BCHEMAPT | |
| Hydrochloric Acid SCHEMBL7621062 | 0.81 | SLC6A2 (0.65) | SLC6A2MAPTMKNK1MKNK2 | |
| SCHEMBL8946085 | 0.79 | SLC6A2 (0.47) | SLC6A2BCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL8946036 | 0.78 | BCHE (0.54) | SLC6A2BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276156-A | Antidepressants, treatment of Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-01-04 | — | — | US | claimed |
| EP-0509400-B1 | 1-(Pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles, intermediates and a process for their preparation, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5519131-A | CYCLIZATION OF HYDROXYALKYLAMINO COMPOUND IN THE PRESENCE OF STRONG BASE SUCH AS SODIUM HYDRIDE OR POTASSIUM TERT-BUTOXIDE | HOECHST MARION ROUSSEL INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5276156-A | Antidepressants, treatment of Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-01-04 | — | — | US | disclosed |
| US-5214038-A | Cholinesterase inhibitors, antidepressants, cognition activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0509400-A1 | 1-(Pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles, intermediates and a process for their preparation, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-10-21 | — | — | EP | disclosed |