Methylpyrrolidone

Methylpyrrolidone

SCHEMBL7609358

CN1CCCC1=O.ClC(Cl)Cl

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.81
BRD2 P25440 1/20 0.81
PIK3CD O00329 2/20 0.42
INMT O95050 2/20 0.41
LMNA P02545 3/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
GAA P10253 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL6590406 0.93 BRD4 (0.77) BRD4BRD2PIK3CDINMTLMNA
Methylpyrrolidone SCHEMBL487 0.90
Methylpyrrolidone SCHEMBL8055062 0.90 BRD4 (1.00) BRD4BRD2PIK3CDINMTLMNA
Methylpyrrolidone SCHEMBL1255511 0.90 BRD4 (1.00) BRD4BRD2PIK3CDINMTLMNA
Methylpyrrolidone SCHEMBL5423326 0.90
Methylpyrrolidone SCHEMBL27899870 0.88 BRD4 (0.85) BRD4BRD2PIK3CDINMTLMNA
Methylpyrrolidone SCHEMBL28183883 0.88
Methylpyrrolidone SCHEMBL9634127 0.88
Methylpyrrolidone SCHEMBL25409888 0.87
Methylpyrrolidone SCHEMBL11649612 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111111479-B Mixed matrix membrane for gas separation and preparation method and application thereof 中国科学院大连化学物理研究所 2021-05-18 CN claimed
CN-111111479-B Mixed matrix membrane for gas separation and preparation method and application thereof 中国科学院大连化学物理研究所 2021-05-18 CN disclosed
CN-111995163-A Treatment method for chloroform in aramid fiber solvent recovery wastewater 沈阳化工研究院设计工程有限公司 2020-11-27 CN disclosed
CN-111111479-A Mixed matrix membrane for gas separation and preparation method and application thereof 中国科学院大连化学物理研究所 2020-05-08 CN disclosed
CN-104284895-B Nitrogenous dicyclic aromatic heterocyclic compounds 安斯泰来制药株式会社 2016-08-31 CN disclosed
CN-104144915-B Nitrogenous aromatic heterocyclic compounds 安斯泰来制药有限公司 2016-08-24 CN disclosed
US-20020131901-A1 Gas sensors BRITISH GAS PLC (GB) 2002-09-19 US disclosed
EP-0637378-B1 GAS SENSORS BRITISH GAS PLC (GB) 2000-04-12 EP disclosed
US-5536473-A Polyaniline gas sensor BRITISH GAS PLC (GB) 1996-07-16 US disclosed
EP-0637378-A1 GAS SENSORS BG Public Limited Company (GB) 1995-02-08 EP disclosed
WO-1994016316-A1 GAS SENSORS BRITISH GAS PLC (GB) 1994-07-21 WO disclosed