Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175979 | 0.79 | IGF1R (0.40) | HTR2ACYP2A6MEN1KMT2ACYP1A2 | |
| SCHEMBL16070654 | 0.79 | IGF1R (0.40) | HTR2ACYP2A6MEN1KMT2ACYP1A2 | |
| SCHEMBL6632793 | 0.79 | HTR2A (0.38) | HTR2ACNR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16070705 | 0.79 | IGF1R (0.40) | HTR2ACYP2A6MEN1KMT2ACYP1A2 | |
| SCHEMBL4661057 | 0.78 | ESR1 (0.44) | CNR1CNR2SLC6A2SLC6A3CHRM2 | |
| SCHEMBL25221462 | 0.77 | HTR2A (0.36) | HTR2ACNR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL502172 | 0.77 | TRPA1 (0.46) | HTR2ACYP1A2ALOX5PYCR1 | |
| SCHEMBL389436 | 0.77 | DPP4 (0.42) | HTR2ACNR1CYP2A6MEN1KMT2A | |
| SCHEMBL22690052 | 0.77 | DPP4 (0.42) | HTR2ACNR1CYP2A6MEN1KMT2A | |
| SCHEMBL537301 | 0.77 | HTR2A (0.36) | HTR2ACNR1CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |