Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565057 | 0.96 | VDR (0.53) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL6563099 | 0.94 | VDR (0.49) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL6562899 | 0.89 | VDR (0.53) | VDRMRGPRX4F2NR4A2FFAR1 | |
| SCHEMBL27568058 | 0.84 | TSHR (0.46) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL7609504 | 0.83 | VDR (0.41) | VDRMRGPRX4F2NR4A2FFAR1 | |
| SCHEMBL6564829 | 0.79 | VDR (0.50) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL6564607 | 0.78 | VDR (0.57) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL6566409 | 0.78 | VDR (0.49) | VDRMRGPRX4F2NR4A2MAOB | |
| SCHEMBL6564194 | 0.76 | VDR (0.50) | VDRMRGPRX4F2FFAR1 | |
| SCHEMBL7608503 | 0.76 | VDR (0.44) | VDRMRGPRX4F2NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |