SCHEMBL7609595

SCHEMBL7609595

O=C(O)C1CCCN(CCCN2c3ccccc3Oc3ccccc32)C1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7609592 1.00 SLC6A1 (0.60) SLC6A1
Hydrochloric Acid SCHEMBL8201665 0.99 SLC6A1 (0.59) SLC6A1
Hydrochloric Acid SCHEMBL8201670 0.99 SLC6A1 (0.59) SLC6A1
SCHEMBL8859092 0.90 SLC6A1 (0.75) SLC6A1
SCHEMBL8859088 0.90 SLC6A1 (0.75) SLC6A1
Hydrochloric Acid SCHEMBL8859051 0.89 SLC6A1 (0.74) SLC6A1
Hydrochloric Acid SCHEMBL8859062 0.89 SLC6A1 (0.74) SLC6A1
SCHEMBL7604123 0.88 SLC6A1 (0.63) SLC6A1
Hydrochloric Acid SCHEMBL8196530 0.87 SLC6A1 (0.62) SLC6A1
SCHEMBL7604305 0.86 SLC6A1 (0.55) SLC6A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1135129-A1 USE OF N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INDICATIONS RELATED TO ANGIOGENESIS NOVO NORDISK A/S (DK) 2001-09-26 EP claimed
WO-2000032193-A1 USE OF N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INDICATIONS RELATED TO ANGIOGENESIS NOVO NORDISK A/S (DK) 2000-06-08 WO claimed
EP-0738262-B1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK AS (DK) 2000-04-19 EP claimed
US-5741791-A ADMINISTERING COMPOUNDS WHICH INHIBIT SECRETION, CIRCULATION OR EFFECT OF INSULIN ANTAGONIZING PEPTIDES; CAN BE USED TO TREAT NON-INSULIN-DEPENDENT DIABETES MELLITUS NOVO NORDISK A/S (DK) 1998-04-21 US claimed
EP-0738262-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1996-10-23 EP claimed
WO-1995018793-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1995-07-13 WO claimed
US-20020045610-A1 Use of N-substituted azaheterocyclic compounds for the manufacture of a pharmaceutical composition for the treatment of indications related to angiogenesis LUBRIZOL CORPORATION, THE 2002-04-18 US disclosed
EP-0869777-A1 NOVEL METHOD NOVO NORDISK A/S (DK) 1998-10-14 EP disclosed
US-5741791-A ADMINISTERING COMPOUNDS WHICH INHIBIT SECRETION, CIRCULATION OR EFFECT OF INSULIN ANTAGONIZING PEPTIDES; CAN BE USED TO TREAT NON-INSULIN-DEPENDENT DIABETES MELLITUS NOVO NORDISK A/S (DK) 1998-04-21 US disclosed
WO-1997022338-A1 NOVEL METHOD NOVO NORDISK A/S (DK) 1997-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045610-A1 Use of N-substituted azaheterocyclic compounds for the manufacture of a pharmaceutical composition for the treatment of indications related to angiogenesis VEGFA, KDR, FLT4 SLC6A1 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.