Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.49 |
| ▸ | ACHE | P22303 | 8/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612385 | 0.94 | BCHE (0.49) | BCHEACHESLC2A1KDM4EALDH1A1 | |
| SCHEMBL7609661 | 0.91 | BCHE (0.47) | BCHEACHESLC2A1KDM4EALDH1A1 | |
| SCHEMBL7620225 | 0.91 | BCHE (0.47) | BCHEACHESLC2A1CA12CA9 | |
| SCHEMBL7606802 | 0.91 | MEN1 (0.52) | BCHEACHESLC2A1KDM4ECA12 | |
| SCHEMBL7681881 | 0.88 | BCHE (0.58) | BCHEACHESLC2A1ALDH1A1MEN1 | |
| SCHEMBL7609658 | 0.87 | SLC2A1 (0.59) | BCHEACHESLC2A1KDM4EALDH1A1 | |
| SCHEMBL7609651 | 0.87 | SLC2A1 (0.59) | BCHEACHESLC2A1KDM4EALDH1A1 | |
| SCHEMBL7612316 | 0.87 | BCHE (0.48) | BCHEACHESLC2A1KDM4EALDH1A1 | |
| SCHEMBL7606658 | 0.86 | BCHE (0.55) | BCHEACHESLC2A1ALDH1A1MEN1 | |
| SCHEMBL7609690 | 0.85 | BCHE (0.58) | BCHEACHESLC2A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |