SCHEMBL7609760

SCHEMBL7609760

CCCN(c1ccncc1)n1cccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 10/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7616450 0.98 SLC6A2 (0.58) SLC6A2
SCHEMBL7612279 0.90 SLC6A2 (0.59) SLC6A2
Hydrochloric Acid SCHEMBL7646053 0.88 SLC6A2 (0.58) SLC6A2
SCHEMBL7610946 0.85 SLC6A2 (0.55) SLC6A2
Hydrochloric Acid SCHEMBL7610918 0.84 SLC6A2 (0.54) SLC6A2
SCHEMBL10570990 0.78 SLC6A2 (0.56) SLC6A2
SCHEMBL8544089 0.77 SLC6A2 (0.61) SLC6A2
SCHEMBL9469234 0.77 SLC6A2 (0.59) SLC6A2
SCHEMBL7610949 0.76 SLC6A2 (0.58) SLC6A2
SCHEMBL7616449 0.75 SLC6A2 (0.57) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP claimed
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US claimed
EP-0840609-A1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1998-05-13 EP claimed
WO-1997004777-A1 USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1997-02-13 WO claimed
US-4900742-A N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1990-02-13 US claimed
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP disclosed
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US disclosed
EP-0840609-A1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1998-05-13 EP disclosed
WO-1997004777-A1 USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1997-02-13 WO disclosed
US-5194618-A Cognition activators for memory enhancers HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1993-03-16 US disclosed
US-5039687-A Learning enhancement, cognition activation HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-08-13 US disclosed
US-5032599-A Learning enhancement HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-07-16 US disclosed
US-4900742-A N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1990-02-13 US disclosed
US-4792562-A N-(pyrrol-1-yl)pyridinamines having memory enhancing activity HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-12-20 US disclosed
US-4752610-A N-(pyrrol-1-yl)pyridinamines having memory enhancing properties HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-06-21 US disclosed
EP-0226099-A2 N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-06-24 EP disclosed