SCHEMBL7616449

SCHEMBL7616449

C#CCN(c1ccncc1)n1cccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7610820 0.98 SLC6A2 (0.56) SLC6A2
SCHEMBL7610946 0.78 SLC6A2 (0.55) SLC6A2
SCHEMBL7613237 0.77 SLC6A2 (0.58) SLC6A2
Hydrochloric Acid SCHEMBL7610918 0.76 SLC6A2 (0.54) SLC6A2
Hydrochloric Acid SCHEMBL7608019 0.76 SLC6A2 (0.57) SLC6A2
SCHEMBL7609760 0.75 SLC6A2 (0.59) SLC6A2
SCHEMBL9469179 0.75 CHRM2 (0.39) SLC6A2
Hydrochloric Acid SCHEMBL7616450 0.74 SLC6A2 (0.58) SLC6A2
SCHEMBL7609755 0.74 CYP19A1 (0.46) SLC6A2
Hydrochloric Acid SCHEMBL9469297 0.74 MEN1 (0.40) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1184969-C Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents AVENTIS PHARMA INC (US) 2005-01-19 CN claimed
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP claimed
CN-1191486-A Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants HOECHST MARION ROUSSEL INC (US) 1998-08-26 CN claimed
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US claimed
EP-0840609-A1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1998-05-13 EP claimed
WO-1997004777-A1 USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1997-02-13 WO claimed
US-5032599-A Learning enhancement HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-07-16 US claimed
CN-1184969-C Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents AVENTIS PHARMA INC (US) 2005-01-19 CN disclosed
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP disclosed
CN-1191486-A Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants HOECHST MARION ROUSSEL INC (US) 1998-08-26 CN disclosed
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US disclosed
US-5194618-A Cognition activators for memory enhancers HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1993-03-16 US disclosed
US-5032599-A Learning enhancement HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-07-16 US disclosed
US-4792562-A N-(pyrrol-1-yl)pyridinamines having memory enhancing activity HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-12-20 US disclosed
EP-0226099-A2 N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-06-24 EP disclosed