Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.60 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | CTRC | Q99895 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607206 | 0.80 | F2 (0.69) | F2F10CTRCPRSS2 | |
| SCHEMBL7607232 | 0.80 | F2 (0.82) | F2F10CTRCPRSS2 | |
| SCHEMBL7522874 | 0.79 | F2 (0.75) | F2F10CTRCPRSS2 | |
| SCHEMBL5866196 | 0.71 | F2 (0.83) | F2F10CTRCPRSS2CACNA1B | |
| Hydrochloric Acid SCHEMBL5866080 | 0.70 | F2 (0.81) | F2F10CTRCPRSS2CACNA1B | |
| SCHEMBL6553380 | 0.69 | F2 (1.00) | F2F10CTRCPRSS2 | |
| SCHEMBL7604953 | 0.69 | F2 (0.77) | F2F10PRSS2CACNA1B | |
| Hydrochloric Acid SCHEMBL6553373 | 0.69 | F2 (0.98) | F2F10CTRCPRSS2 | |
| SCHEMBL5866292 | 0.66 | F2 (0.60) | F2F10PRSS2CACNA1B | |
| SCHEMBL5866370 | 0.66 | F2 (0.58) | F2F10CTRCPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917528-B1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | EP | claimed |