Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233737 | 0.96 | HSD17B10 (0.54) | ACACBHSD17B10MAPTRXFP1SIGMAR1 | |
| SCHEMBL7609058 | 0.83 | PDE4B (0.48) | ACACBHSD17B10MAPTSIGMAR1SMN1; SMN2 | |
| SCHEMBL8471831 | 0.83 | PDE4B (0.48) | ACACBHSD17B10MAPTSIGMAR1SMN1; SMN2 | |
| SCHEMBL14819227 | 0.82 | HSD17B10 (0.54) | HSD17B10MAPTRXFP1SIGMAR1SMN1; SMN2 | |
| SCHEMBL8476620 | 0.82 | MAPT (0.42) | HSD17B10MAPTRXFP1SIGMAR1SMN1; SMN2 | |
| SCHEMBL7603010 | 0.82 | MAPT (0.42) | HSD17B10MAPTRXFP1SIGMAR1SMN1; SMN2 | |
| SCHEMBL11239470 | 0.80 | USP5 (0.53) | ACACBHSD17B10MAPTSIGMAR1SMN1; SMN2 | |
| SCHEMBL8959741 | 0.80 | MAPT (0.59) | HSD17B10MAPTRXFP1SMN1; SMN2HDAC3 | |
| SCHEMBL11237800 | 0.80 | HSD17B10 (0.46) | HSD17B10MAPTRXFP1SIGMAR1SMN1; SMN2 | |
| SCHEMBL764976 | 0.79 | MAPT (0.62) | HSD17B10MAPTRXFP1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820984-B1 | Activated amphetamines | ROCHE DIAGNOSTICS GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0820984-A1 | Activated amphetamines | Roche Diagnostics GmbH (DE) | 1998-01-28 | — | — | EP | disclosed |