SCHEMBL7611361

SCHEMBL7611361

O=C(O)Cc1cccc(-c2cc(Cc3cc(Cc4ccc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)c(-c5cccc(CC(=O)O)c5)c4)cc(Cc4ccc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)c(-c5cccc(CC(=O)O)c5)c4)c3)ccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)c1

nearest known ligand 0.81

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SELP P16109 2/20 0.81
▸ SELPLG Q14242 1/20 0.81
▸ SLC5A2 P31639 8/20 0.49
▸ PLA2G10 O15496 1/20 0.45
▸ PLA2G2A P14555 1/20 0.45
▸ ACHE P22303 1/20 0.45
▸ SLC28A3 Q9HAS3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8205205 0.90 SELP (0.98) SELPSELPLGSLC5A2ACHESLC28A3
SCHEMBL13390119 0.90 SELP (0.81) SELPSELPLGSLC5A2ACHESLC28A3
SCHEMBL7619803 0.90 SELP (0.98) SELPSELPLGSLC5A2ACHESLC28A3
Bimosiamose SCHEMBL12182030 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
Bimosiamose SCHEMBL29367817 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
Bimosiamose SCHEMBL29372538 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
SCHEMBL7614341 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
Bimosiamose SCHEMBL2529148 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
SCHEMBL7620761 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3
Bimosiamose SCHEMBL14015902 0.90 SELP (1.00) SELPSELPLGSLC5A2ACHESLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020132220-A1 Use of selectin antagonists in organ preservation solutions TEXAS BIOTECHNOLOGY CORPORATION 2002-09-19 — — US claimed
EP-0840606-B1 DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS TEXAS BIOTECHNOLOGY CORP (US) 2000-06-07 — — EP claimed
US-5919768-A COMPOUNDS WHICH INHIBIT BINDING OF SELECTINS TO SIALYL-LEWIS-X AND SIALYL-LEWIS-A CARBOHYDRATES TEXAS BIOTECHNOLOGY CORPORATION (US) 1999-07-06 — — US claimed
US-20020132220-A1 Use of selectin antagonists in organ preservation solutions TEXAS BIOTECHNOLOGY CORPORATION 2002-09-19 — — US disclosed
EP-0840606-B1 DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS TEXAS BIOTECHNOLOGY CORP (US) 2000-06-07 — — EP disclosed
US-5919768-A COMPOUNDS WHICH INHIBIT BINDING OF SELECTINS TO SIALYL-LEWIS-X AND SIALYL-LEWIS-A CARBOHYDRATES TEXAS BIOTECHNOLOGY CORPORATION (US) 1999-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020132220-A1 Use of selectin antagonists in organ preservation solutions SELE, SELPLG, SELL SELP 4/4885SELPLG 2/4885SLC5A2 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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