Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.54 |
| ▸ | ITGAL | P20701 | 6/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7610286 | 0.78 | ITGB2 (0.68) | ITGB2ICAM1ITGALTSHRCYP3A4 | |
| SCHEMBL7612648 | 0.76 | ITGB2 (0.65) | ITGB2ICAM1ITGALTSHRCYP3A4 | |
| SCHEMBL7610147 | 0.76 | IDO1 (0.53) | ITGB2ICAM1ITGALTSHRALDH1A1 | |
| SCHEMBL3165346 | 0.75 | ITGB2 (0.72) | ITGB2ICAM1ITGALTSHRCYP3A4 | |
| SCHEMBL7611442 | 0.75 | ITGB2 (0.53) | ITGB2ICAM1ITGALCYP3A4ALDH1A1 | |
| SCHEMBL7610324 | 0.72 | ITGB2 (0.96) | ITGB2ICAM1ITGALTSHRCYP3A4 | |
| SCHEMBL7611543 | 0.72 | ITGB2 (0.31) | ITGB2ICAM1ITGAL | |
| SCHEMBL3075750 | 0.72 | CYP3A4 (0.52) | TSHRCYP3A4ALDH1A1MAPTKMT2A | |
| SCHEMBL29464137 | 0.72 | CYP3A4 (0.52) | TSHRCYP3A4ALDH1A1MAPTKMT2A | |
| SCHEMBL1980735 | 0.72 | ALDH1A1 (0.53) | TSHRCYP3A4ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165504-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059878-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2000-10-12 | — | — | WO | disclosed |