Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | MTTP | P55157 | 6/20 | 0.49 |
| ▸ | APOB | P04114 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605521 | 0.92 | RXFP1 (0.55) | ROCK2GRK2MTTPAPOBKDM1A | |
| SCHEMBL7606603 | 0.91 | CES1 (0.55) | ROCK2GRK2MTTPAPOBKDM1A | |
| SCHEMBL7613634 | 0.90 | ROCK2 (0.56) | ROCK2GRK2MTTPAPOBKDM1A | |
| SCHEMBL7608096 | 0.90 | ROCK2 (0.50) | ROCK2GRK2MTTPAPOBKDM1A | |
| SCHEMBL7613600 | 0.88 | MTTP (0.58) | MTTPAPOBPPARGRXFP1EPHX2 | |
| SCHEMBL7607440 | 0.88 | MTTP (0.57) | MTTPAPOBKDM1AHDAC1PPARG | |
| SCHEMBL7607886 | 0.87 | EPHX2 (0.58) | ROCK2GRK2MTTPAPOBKDM1A | |
| SCHEMBL7607269 | 0.86 | EPHX2 (0.57) | MTTPAPOBPPARGEPHX2NAMPT | |
| SCHEMBL6788420 | 0.86 | MTTP (0.57) | ROCK2MTTPAPOBKDM1AHDAC1 | |
| SCHEMBL7650666 | 0.86 | MTTP (0.49) | ROCK2GRK2MTTPAPOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | ROCK2 4734/4885GRK2 3440/4885MTTP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.