Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611707 | 1.00 | HDAC6 (0.54) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL7612898 | 1.00 | HDAC6 (0.54) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL8592486 | 0.93 | HDAC6 (0.58) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL8545269 | 0.93 | HDAC6 (0.58) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL17864250 | 0.79 | HDAC6 (0.61) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL7636868 | 0.79 | CCNT1 (0.45) | HDAC6CCNT1CDK9 | |
| SCHEMBL7608516 | 0.79 | CCNT1 (0.45) | HDAC6CCNT1CDK9 | |
| SCHEMBL7608514 | 0.79 | CCNT1 (0.45) | HDAC6CCNT1CDK9 | |
| SCHEMBL7611727 | 0.79 | CCNT1 (0.45) | HDAC6CCNT1CDK9 | |
| SCHEMBL17864240 | 0.78 | HDAC6 (0.60) | HDAC6CCNT1CDK9TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO WELLCOME INC. | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | ZC3HAV1, BRPF3, BRD3 | HDAC6 44/4885CCNT1 483/4885CDK9 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.