Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327227 | 0.71 | HRH3 (0.48) | HTTSMN1; SMN2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10061231 | 0.68 | — | — | |
| SCHEMBL15886127 | 0.66 | HTT (0.44) | HTTSMN1; SMN2ALDH1A1MAPK1HRH4 | |
| SCHEMBL22279103 | 0.66 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2HRH4CYP1A2HSD17B10 | |
| SCHEMBL15886057 | 0.64 | HTT (0.43) | HTTSMN1; SMN2ALDH1A1MAPK1HRH4 | |
| SCHEMBL7647201 | 0.64 | SMPD3 (0.42) | SMN1; SMN2HRH4CRHBPCRHR2 | |
| SCHEMBL7647192 | 0.64 | SMPD3 (0.42) | SMN1; SMN2HRH4CRHBPCRHR2 | |
| SCHEMBL20377814 | 0.62 | SMN1; SMN2 (0.42) | HTTSMN1; SMN2ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL16134879 | 0.62 | CYP1A2 (0.57) | ALDH1A1HRH4CYP1A2KDM4E | |
| SCHEMBL15885896 | 0.62 | HTT (0.41) | HTTSMN1; SMN2ALDH1A1MAPK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074267-A1 | NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |