Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647201 | 1.00 | SMPD3 (0.42) | SMPD3HRH4PARP1CRHBPCRHR2 | |
| SCHEMBL15360080 | 0.74 | SMPD3 (0.42) | SMPD3HRH4PARP1SMN1; SMN2HTR3E | |
| SCHEMBL7646554 | 0.71 | PIK3CB (0.39) | — | |
| SCHEMBL7646558 | 0.71 | PIK3CB (0.39) | — | |
| SCHEMBL7644422 | 0.67 | NNMT (0.32) | PDE10A | |
| SCHEMBL12231513 | 0.66 | HTR3A (0.44) | HRH4PARP1SMN1; SMN2HRH3HTR3E | |
| SCHEMBL15886127 | 0.65 | HTT (0.44) | SMPD3HRH4CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL7641627 | 0.64 | KMT2A (0.47) | PARP1SMN1; SMN2 | |
| SCHEMBL7641636 | 0.64 | KMT2A (0.47) | PARP1SMN1; SMN2 | |
| SCHEMBL7612236 | 0.64 | HTT (0.41) | HRH4CRHBPCRHR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074267-A1 | NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |