Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791085 | 0.88 | NR1H2 (0.34) | ESR1TP53ALDH1A1KCNH2NR1H2 | |
| SCHEMBL6787475 | 0.82 | SOAT1 (0.38) | ICMTALB | |
| SCHEMBL5716462 | 0.82 | SOAT1 (0.35) | ALDH1A1ICMTALBMEN1KMT2A | |
| SCHEMBL5716436 | 0.82 | NR1H2 (0.38) | ESR1NR1H2NR1H3 | |
| SCHEMBL5715943 | 0.80 | NPC1 (0.44) | KCNH2SIGMAR1NR1H2NR1H3ICMT | |
| SCHEMBL5715726 | 0.80 | NPC1 (0.44) | KCNH2SIGMAR1NR1H2NR1H3ICMT | |
| SCHEMBL10621236 | 0.77 | KCNH2 (0.41) | ESR1TP53ALDH1A1KCNH2ICMT | |
| SCHEMBL6790311 | 0.76 | SLC6A2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL5715484 | 0.75 | MEN1 (0.31) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10620514 | 0.75 | ESR1 (0.41) | ESR1TP53ALDH1A1KCNH2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252166-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001042249-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2001-06-14 | — | — | WO | disclosed |