SCHEMBL6791085

SCHEMBL6791085

CCCCCCCCCN(c1cccc(F)c1F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
ICMT O60725 2/20 0.32
EPHX2 P34913 1/20 0.32
ESR1 P03372 1/20 0.32
KCNH2 Q12809 7/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716436 0.94 NR1H2 (0.38) NR1H2NR1H3DRD2DRD3ESR1
SCHEMBL7612249 0.88 ESR1 (0.38) NR1H2NR1H3MEN1KMT2ASMN1; SMN2
SCHEMBL5715484 0.87 MEN1 (0.31) MEN1KMT2ASMN1; SMN2DRD2DRD3
SCHEMBL5716561 0.84 DRD2 (0.32) NR1H2NR1H3MEN1KMT2ASMN1; SMN2
SCHEMBL5716009 0.83 ALDH1A1 (0.33) NR1H2NR1H3ALDH1A1
SCHEMBL5716213 0.79 MEN1 (0.36) NR1H2NR1H3MEN1KMT2ASMN1; SMN2
SCHEMBL6798338 0.79 MEN1 (0.36) NR1H2NR1H3MEN1KMT2ASMN1; SMN2
SCHEMBL5715946 0.77 MEN1 (0.37) MEN1KMT2ASMN1; SMN2DRD2DRD3
SCHEMBL5715959 0.77 MEN1 (0.37) MEN1KMT2ASMN1; SMN2DRD2DRD3
SCHEMBL5716207 0.77 NR1H2 (0.37) NR1H2NR1H3MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed