Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.80 |
| ▸ | PGR | P06401 | 3/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | IKBKB | O14920 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114530 | 1.00 | NR3C1 (0.85) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL9797346 | 0.92 | HIF1A (0.78) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL9797354 | 0.92 | HIF1A (0.78) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL11309009 | 0.92 | HIF1A (0.78) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL18379414 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL3754621 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL16718939 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL22028449 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL19764184 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA | |
| SCHEMBL13929942 | 0.92 | NR3C1 (1.00) | NR3C1HIF1ACYP3A4HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902789-B1 | ANDROSTENE DERIVATIVES | SOFT DRUGS INC (US) | 2002-01-23 | — | — | EP | disclosed |
| US-5801165-A | Antiinflammatory, immunosuppressive and antialleric 16, 17-alkylidioxy-steroids | RHONE-POULENC RORER LIMITED (GB) | 1998-09-01 | — | — | US | disclosed |
| EP-0675897-B1 | NEW STEROIDS | RHONE POULENC RORER LTD (GB) | 1997-06-18 | — | — | EP | disclosed |