Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 15/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620000 | 0.89 | ITGAL (0.47) | ITGALITGB2ICAM1KMT2A | |
| SCHEMBL6197946 | 0.87 | ITGAL (0.72) | ITGALITGB2ICAM1KMT2A | |
| SCHEMBL7624289 | 0.85 | ITGAL (0.75) | ITGALITGB2ICAM1 | |
| SCHEMBL6197945 | 0.82 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL7618237 | 0.82 | ITGAL (0.49) | ITGALITGB2ICAM1 | |
| SCHEMBL7624300 | 0.81 | ITGAL (0.74) | ITGALITGB2ICAM1 | |
| SCHEMBL7612983 | 0.80 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL7616863 | 0.80 | ITGAL (0.49) | ITGALITGB2ICAM1 | |
| SCHEMBL7611696 | 0.79 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL6196751 | 0.78 | ITGB2 (0.44) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |