Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 16/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 12/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.49 |
| ▸ | ANPEP | P15144 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491647 | 0.88 | ITGAL (0.64) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL6200575 | 0.88 | ITGAL (0.64) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL7616863 | 0.87 | ITGAL (0.49) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL6200571 | 0.84 | ITGAL (0.34) | ITGALITGB2ICAM1 | |
| SCHEMBL7611696 | 0.83 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL7620000 | 0.82 | ITGAL (0.47) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL7612914 | 0.82 | ITGAL (0.55) | ITGALITGB2ICAM1 | |
| SCHEMBL6200562 | 0.81 | ITGB2 (0.42) | ITGALITGB2ICAM1 | |
| SCHEMBL7624300 | 0.80 | ITGAL (0.74) | ITGALITGB2ICAM1 | |
| SCHEMBL7612983 | 0.79 | ITGAL (0.62) | ITGALITGB2ICAM1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | claimed |