⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15907848 | 0.63 | PNP (0.41) | — | |
| SCHEMBL7672758 | 0.61 | PNP (0.48) | — | |
| SCHEMBL5158035 | 0.59 | — | — | |
| SCHEMBL3180710 | 0.58 | CDK1 (0.52) | — | |
| SCHEMBL5174334 | 0.56 | — | — | |
| SCHEMBL215067 | 0.53 | — | — | |
| SCHEMBL4466079 | 0.53 | — | — | |
| SCHEMBL3956367 | 0.53 | — | — | |
| SCHEMBL5157876 | 0.53 | — | — | |
| SCHEMBL9386099 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380165-B1 | THAT IS ANTIGENIC AND USEFUL FOR FORMING ANTIBODIES HAVING UTILITY IN STANDARDIZING DIAGNOSTIC ASSAYS, COMPRISING A LYSINE COMPONENT, AN ARGININE COMPONENT AND A REDUCING SUGAR COMPONENT | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH | 2002-04-30 | — | — | US | disclosed |
| US-20020022234-A1 | IMMUNOLOGICAL ADVANCED GLYCATION ENDPRODUCT CROSSLINK | PICOWER INSTITUTE FOR MEDICAL RESEARCH | 2002-02-21 | — | — | US | disclosed |
| EP-1018005-A1 | METHODS FOR MEASURING AND ELIMINATING ADVANCED GLYCATION ENDPRODUCTS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014587-A1 | METHODS FOR MEASURING AND ELIMINATING ADVANCED GLYCATION ENDPRODUCTS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1999-03-25 | — | — | WO | disclosed |