Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104506 | 0.81 | IDO1 (0.36) | ALOX15 | |
| SCHEMBL3163728 | 0.81 | SMN1; SMN2 (0.42) | SRCAKR1B1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL29126683 | 0.81 | RXRA (0.51) | SRCAKR1B1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL15780476 | 0.80 | SRC (0.62) | SRCAKR1B1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL16831106 | 0.78 | SLC6A4 (0.42) | — | |
| SCHEMBL2006540 | 0.77 | AKR1B1 (0.43) | SRCAKR1B1PTGS2CYP1A2RXRA | |
| SCHEMBL2335889 | 0.77 | PTPRC (0.46) | SRCAKR1B1MAPTHSD17B10CYP1A2 | |
| SCHEMBL29126669 | 0.77 | IDO1 (0.49) | SRCAKR1B1PTGS2PTGS1CAMK2A | |
| SCHEMBL5970108 | 0.77 | HSD17B10 (0.68) | HSD17B10MEN1KMT2A | |
| Rubidium SCHEMBL38664121 | 0.76 | AKR1B1 (0.38) | SRCAKR1B1MAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171113-A1 | COMPOUNDS USEFUL AS PHOSPHOTYROSINE MIMICS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000062770-A1 | COMPOUNDS USEFUL AS PHOSPHOTYROSINE MIMICS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |