Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528135 | 0.98 | RARB (0.68) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL5400573 | 0.91 | MAPK1 (0.73) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL8432243 | 0.91 | MAPK1 (0.73) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL9808804 | 0.87 | RARB (0.70) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL8436176 | 0.86 | TP53 (0.58) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL8072342 | 0.86 | TP53 (0.58) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL9319143 | 0.85 | KMT2A (0.69) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL5091731 | 0.85 | TP53 (0.60) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL13953004 | 0.85 | TP53 (0.60) | RARBMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL4602775 | 0.85 | TP53 (0.60) | RARBMAPK1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882085-B1 | BIODEGRADABLE POLYMER NETWORKS FOR USE IN ORTHOPEDIC AND DENTAL APPLICATIONS | MASSACHUSETTS INST TECHNOLOGY (US) | 2002-07-24 | — | — | EP | disclosed |