Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | RARB | P10826 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400573 | 1.00 | MAPK1 (0.73) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL7613153 | 0.91 | RARB (0.69) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL20528135 | 0.89 | RARB (0.68) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL9319143 | 0.88 | KMT2A (0.69) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL9487296 | 0.88 | MAPK1 (0.58) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL13556990 | 0.87 | MAPK1 (0.73) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL8080304 | 0.85 | MAPK1 (0.57) | MAPK1RARBKMT2ATSHRTP53 | |
| SCHEMBL6538723 | 0.85 | MAPK1 (1.00) | MAPK1RARBKMT2APKMTSHR | |
| SCHEMBL14539465 | 0.84 | MAPK1 (0.69) | MAPK1RARBPKMTSHRTP53 | |
| SCHEMBL7995208 | 0.83 | KMT2A (0.62) | MAPK1RARBKMT2ATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008401-A | CONDENSATION REACTION BETWEEN 4-HALO OR NITRO SUBSTITUTED BENZONITRILE DERIVATIVE AND OTICALLY ACTIVE ALCOHOL PRODUCES AN OPTICALLY ACTIVE ALKOXYBENZONITRILE DERIVATIVE | NIPPON OIL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |