⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762774 | 0.90 | — | — | |
| SCHEMBL28325272 | 0.89 | — | — | |
| SCHEMBL17307699 | 0.88 | FKBP5 (0.43) | — | |
| Bromide SCHEMBL19066250 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL28236204 | 0.88 | — | — | |
| SCHEMBL10069784 | 0.88 | — | — | |
| SCHEMBL8736493 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL28104524 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8003961 | 0.88 | — | — | |
| SCHEMBL31323236 | 0.81 | FKBP5 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119656330-A | Preparation of supermolecule nanoparticle for self-assembly of stimulus-responsive polypeptide coupled drug and application of supermolecule nanoparticle in brain tumor | 北京理工大学 | 2025-03-21 | — | — | CN | claimed |
| CN-117088869-A | 3CL protease inhibitor and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | claimed |
| CN-113135956-A | Mitochondrion targeted curcumin derivative and preparation method and medical application thereof | 蔡世忠 | 2021-07-20 | — | — | CN | claimed |
| CN-112500419-A | Epoxy fused 2-methylene pyrrolidine compound and preparation method thereof | 浙大城市学院 | 2021-03-16 | — | — | CN | claimed |
| EP-3307724-B1 | (Z)-2-(1H-INDOL-3-YL)-3-(ISOQUINOLIN-5-YL)ACRYLONITRILE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOSOME INHIBITORY AND ANTI-MITOTIC ACTIVITY FOR TREATING HYPERPROLIFERATIVE DISEASES | NAT UNIV SINGAPORE (SG) | 2020-06-10 | — | — | EP | claimed |
| US-10308631-B2 | Selective anti-cancer compounds | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2019-06-04 | — | — | US | claimed |
| US-20180179178-A1 | SELECTIVE ANTI-CANCER COMPOUNDS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2018-06-28 | — | — | US | claimed |
| EP-3307724-A1 | SELECTIVE ANTI-CANCER COMPOUNDS | National University of Singapore (SG) | 2018-04-18 | — | — | EP | claimed |
| WO-2016200339-A1 | SELECTIVE ANTI-CANCER COMPOUNDS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-12-15 | — | — | WO | claimed |
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | claimed |
| WO-2008020711-A1 | QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-02-21 | — | — | WO | claimed |
| EP-0437185-B1 | Pyrroline-resp. indoline containing phthalides | CIBA GEIGY AG (CH) | 1995-10-18 | — | — | EP | claimed |
| US-20250171456-A1 | PSYCHEDELIC COMPOUNDS AND THEIR THERAPEUTIC USES | CAAMTECH INC (US) | 2025-05-29 | — | — | US | disclosed |
| CN-119656330-A | Preparation of supermolecule nanoparticle for self-assembly of stimulus-responsive polypeptide coupled drug and application of supermolecule nanoparticle in brain tumor | 北京理工大学 | 2025-03-21 | — | — | CN | disclosed |
| EP-4472629-A2 | PSYCHEDELIC COMPOUNDS AND THEIR THERAPEUTIC USES | Caamtech, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-4287199-A | USEFUL AS ANTHELMINITICS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |
| US-4260606-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4242261-A | REACTING AN A,A-DIPHENYL-A-N-HETEROCYCLIC ACETAMIDE WITH BROMINE AND AN ALKALI METAL ALKOXIDE AND HEATING | A. H. ROBINS COMPANY, INC. (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0010242-A1 | Benzimidazolyl-2-carbamic acid esters, medicaments based thereon and process for their preparation | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |