SCHEMBL7613367

SCHEMBL7613367

CC(=O)c1cccc(Oc2cccc(C(C)=O)c2C(C)=O)c1C(C)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
LMNA P02545 5/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
THRB P10828 1/20 0.45
HTT P42858 1/20 0.43
MAPK1 P28482 2/20 0.42
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
BLM P54132 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857330 0.87 CTNNB1 (0.54) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL4398297 0.87 KDM4E (0.46) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL2986261 0.86 CA9 (0.59) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL9639967 0.85 KDM4E (0.43) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL4393219 0.85 KMT2A (0.39) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL8443029 0.84 KMT2A (0.46) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL29080260 0.82 KMT2A (0.49) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL10831160 0.82 KMT2A (0.45) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL600052 0.82 THRB (0.56) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL10831162 0.81 KMT2A (0.44) KMT2ALMNAKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020007029-A1 Novel polyester resins ZAITSEY BORIS A (RU) 2002-01-17 US disclosed
EP-1129116-A1 NOVEL POLYMERIZABLE MATERIALS AND NOVEL POLYESTER RESINS Zaitsev, Boris A. (RU) 2001-09-05 EP disclosed
US-6258909-B1 Polyester resins ZAITSEV BORIS A (RU) 2001-07-10 US disclosed
US-6143922-A NOVEL DIOL COMPOSITIONS, NOVEL UNSATURATED MONOMERS, NOVEL RESINS, NOVEL CROSSLINKED POLYMERS, NOVEL POLYESTER POLYMERS, NOVEL POLYESTER POLYMERS THAT DISPLAY IMPROVEMENT OVER ROLIVSAN RESINS ZAITSEV BORIS A (RU) 2000-11-07 US disclosed
WO-2000023485-A1 NOVEL POLYMERIZABLE MATERIALS AND NOVEL POLYESTER RESINS ZAITSEV BORIS A (RU) 2000-04-27 WO disclosed
US-5098990-A Reaction of a dialcohol, a diamine or a diacyl aromatic compound with a bis/trichloromethyl ketone THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
US-4731484-A Haloacetyl derivatives of aromatic compounds THE DOW CHEMICAL COMPANY (US) 1988-03-15 US disclosed
US-4036818-A Method of preparing polymers of polyphenylene type KORSHAK VASILY VLADIMIROVICH 1977-07-19 US disclosed