SCHEMBL761345

SCHEMBL761345

CC(C)(C)CC1OC(CC(C)(C)C)OC(CC(C)(C)C)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10045671 0.84
SCHEMBL10717160 0.79
SCHEMBL18195576 0.78
SCHEMBL20411944 0.71
SCHEMBL16938112 0.71
SCHEMBL2625531 0.71 THRA (0.30)
SCHEMBL13967280 0.71
SCHEMBL2625528 0.67
SCHEMBL19021524 0.67
SCHEMBL25306634 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620458-B1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-alpha-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE DIMETHYL ACETAL AS A PRECURSOR NUTRASWEET PROPERTY HOLDINGS INC (US) 2012-03-21 EP disclosed
US-8034969-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2011-10-11 US disclosed
US-8034969-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2011-10-11 US disclosed
US-8034969-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2011-10-11 US disclosed
US-20100222608-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2010-09-02 US disclosed
US-20100222608-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2010-09-02 US disclosed
US-20100222608-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2010-09-02 US disclosed
EP-2138506-A2 Synthesis of N-N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors The NutraSweet Company (US) 2009-12-30 EP disclosed
US-20080045744-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2008-02-21 US disclosed
US-20080045744-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2008-02-21 US disclosed
US-20080045744-A1 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS THE NUTRASWEET COMPANY (US) 2008-02-21 US disclosed
US-7288670-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2007-10-30 US disclosed
US-7288670-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2007-10-30 US disclosed
US-7288670-B2 Synthesis of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors THE NUTRASWEET COMPANY (US) 2007-10-30 US disclosed
EP-1620458-A2 SYNTHESIS OF N- [N-(3,3-DIMETHYLBUTYL)-L-a-ASPARTYL] -L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS The NutraSweet Company (US) 2006-02-01 EP disclosed
WO-2004101604-A2 SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS NUTRASWEET COMPANY (US) 2004-11-25 WO disclosed
US-20040236140-A1 Synthesis of N-[N-(3,3-dimethylbutyl)-L-alpha-aspartyl]-L-phenylalanine 1-methyl ester using 3,3-dimethylbutyraldehyde precursors NUTRASWEET COMPANY 2004-11-25 US disclosed