Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.69 |
| ▸ | ECE1 | P42892 | 12/20 | 0.61 |
| ▸ | MME | P08473 | 11/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764208 | 1.00 | ACE2 (0.69) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL24991304 | 1.00 | ACE2 (0.69) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7613146 | 1.00 | ACE2 (0.69) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL6923615 | 0.92 | ACE2 (0.58) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7619363 | 0.91 | ACE2 (0.68) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7619360 | 0.91 | ACE2 (0.68) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7620840 | 0.91 | ACE2 (0.68) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7615297 | 0.88 | ECE1 (0.76) | ACE2ECE1MME | |
| SCHEMBL6928872 | 0.88 | ACE2 (0.66) | ACE2ECE1MMEMMP2MMP9 | |
| SCHEMBL7611003 | 0.85 | ANPEP (0.54) | ACE2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073664-B1 | (ALPHA-AMINOPHOSPHINO) PEPTIDESDERIVATIVE AND COMPOSITIONS CONTAINING SAME | INST NAT SANTE RECH MED (FR) | 2002-10-23 | — | — | EP | disclosed |
| US-6391866-B1 | ANALGESICS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-05-21 | — | — | US | disclosed |