Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.49 |
| ▸ | HRH2 | P25021 | 14/20 | 0.49 |
| ▸ | HRH1 | P35367 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622791 | 0.79 | HRH3 (0.59) | HRH3HRH2HRH1 | |
| SCHEMBL7250583 | 0.78 | HRH3 (0.55) | HRH3HRH2HRH1 | |
| SCHEMBL1978291 | 0.77 | HRH3 (0.71) | HRH3HRH2HRH1 | |
| SCHEMBL6093646 | 0.75 | HRH3 (0.81) | HRH3HRH2HRH1 | |
| SCHEMBL7245291 | 0.74 | HRH3 (0.48) | HRH3HRH2HRH1 | |
| SCHEMBL6095921 | 0.73 | HRH3 (0.56) | HRH3HRH2HRH1 | |
| SCHEMBL7252155 | 0.73 | KCNA5 (0.48) | HRH3HRH2HRH1 | |
| SCHEMBL7245870 | 0.73 | HRH2 (0.45) | HRH3HRH2HRH1 | |
| Oxalic Acid SCHEMBL4495391 | 0.72 | HRH3 (0.56) | HRH3HRH2HRH1 | |
| SCHEMBL4491586 | 0.72 | HRH3 (0.68) | HRH3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244631-A1 | NEW AZABICYCLOOCTANE DERIVATIVES USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047893-A1 | NEW AZABICYCLOOCTANE DERIVATIVES USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-07-05 | — | — | WO | disclosed |