Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168594 | 0.97 | GSR (0.44) | GSRRNPEPUSP2SLCO1B1PDE4A | |
| SCHEMBL1167729 | 0.97 | GSR (0.44) | GSRRNPEPUSP2SLCO1B1PDE4A | |
| SCHEMBL1168277 | 0.97 | GSR (0.44) | GSRRNPEPUSP2SLCO1B1PDE4A | |
| SCHEMBL1168214 | 0.86 | GSR (0.38) | GSRUSP2SLCO1B1GNAI3GNAO1 | |
| SCHEMBL1234805 | 0.86 | GSR (0.38) | GSRUSP2SLCO1B1GNAI3GNAO1 | |
| SCHEMBL1168908 | 0.85 | GSR (0.42) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| SCHEMBL22209237 | 0.82 | GSR (0.48) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| SCHEMBL17843610 | 0.82 | GSR (0.48) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| SCHEMBL1168273 | 0.82 | GSR (0.42) | GSRRNPEPUSP2GNAI3GNAO1 | |
| SCHEMBL17797760 | 0.81 | USP2 (0.44) | USP2SLCO1B1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021175-A4 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CT (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1085885-A4 | METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION | FOX CHASE CANCER CT (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1085885-A2 | METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION | FOX CHASE CANCER CENTER (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1021175-A1 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CENTER (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999064561-A2 | METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION | FOX CHASE CANCER CENTER (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998033492-A1 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CENTER (US) | 1998-08-06 | — | — | WO | disclosed |