Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KYNU | Q16719 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.31 |
| ▸ | PGK1 | P00558 | 2/20 | 0.31 |
| ▸ | PGK2 | P07205 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403086 | 0.86 | HDAC4 (0.37) | POLBKYNUHIF1APGK1PGK2 | |
| SCHEMBL7615036 | 0.82 | INPPL1 (0.36) | POLBKDM4EGAAHTR2A | |
| SCHEMBL7621621 | 0.81 | POLB (0.32) | POLBKYNUHIF1APGK1PGK2 | |
| SCHEMBL6402836 | 0.81 | HDAC4 (0.41) | POLBKYNUHIF1APGK1PGK2 | |
| SCHEMBL6395617 | 0.76 | HDAC4 (0.40) | POLBKYNUHIF1APGK1PGK2 | |
| SCHEMBL6397731 | 0.75 | SLC22A1 (0.36) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6396477 | 0.73 | ESR1 (0.49) | ADRA1ATSHRDRD1DRD3SLC6A3 | |
| SCHEMBL7615976 | 0.71 | INPPL1 (0.34) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6403761 | 0.69 | ESR1 (0.46) | ADRA1ADRD1DRD3SLC6A3LMNA | |
| SCHEMBL6402288 | 0.69 | HDAC4 (0.38) | POLBKYNUHIF1AADRB1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175425-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000043402-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-27 | — | — | WO | disclosed |