Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KYNU | Q16719 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620812 | 0.88 | ESR1 (0.38) | ESR1ESR2 | |
| SCHEMBL6395780 | 0.86 | ESR1 (0.38) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL7615976 | 0.81 | INPPL1 (0.34) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL7614967 | 0.81 | POLB (0.32) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6403717 | 0.80 | ADRB1 (0.39) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL7625093 | 0.77 | ESR1 (0.41) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6402386 | 0.75 | ESR1 (0.38) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6394487 | 0.75 | ADRB1 (0.37) | POLBKYNUHIF1AADRB1ADRA1A | |
| SCHEMBL6402444 | 0.73 | ESR1 (0.51) | ADRA1AESR1ESR2DRD1DRD3 | |
| SCHEMBL7615036 | 0.71 | INPPL1 (0.36) | POLBKDM4EGAAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175425-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000043402-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-27 | — | — | WO | disclosed |