Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 7/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615059 | 1.00 | TYMP (0.59) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL7895839 | 0.93 | TYMP (0.69) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL7615405 | 0.93 | TYMP (0.57) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL7615396 | 0.93 | TYMP (0.57) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL7896974 | 0.92 | TYMP (0.56) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL7746133 | 0.92 | TYMP (0.56) | TYMPADORA1CA5ANT5ELMNA | |
| SCHEMBL1895609 | 0.92 | TYMP (0.60) | TYMPADORA1NT5E | |
| SCHEMBL1895610 | 0.92 | TYMP (0.60) | TYMPADORA1NT5E | |
| SCHEMBL18042131 | 0.88 | ADORA1 (0.64) | TYMPADORA1NT5E | |
| SCHEMBL8609998 | 0.88 | CA5A (0.54) | TYMPADORA1CA5ANT5ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198592-A4 | OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES | ISIS PHARMACEUTICALS INC (US) | 2002-09-18 | — | — | EP | disclosed |
| EP-1198592-A1 | OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2002-04-24 | — | — | EP | disclosed |
| EP-1109825-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS INC (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-1109825-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS, INC. (US) | 2001-06-27 | — | — | EP | disclosed |
| US-6175004-B1 | REACTING AN OLIGONUCLEOTIDE COMPRISING A HALOGENATED PURINE NUCLEOSIDE WITH AMINE; FOR STRONGER HYBRIDIZATION; DIAGNOSIS; GENETIC ENGINEERING; ANTISENSE AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |
| WO-2001002608-A1 | OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000012563-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-09 | — | — | WO | disclosed |