Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059912 | 0.73 | — | — | |
| SCHEMBL12279297 | 0.72 | SLC7A5 (0.33) | CYP3A4GRIA2CYP1A2SLC7A5 | |
| SCHEMBL6338009 | 0.72 | SLC7A5 (0.33) | CYP3A4GRIA2CYP1A2SLC7A5 | |
| SCHEMBL12279581 | 0.72 | SLC7A5 (0.33) | CYP3A4GRIA2CYP1A2SLC7A5 | |
| Tyrosine SCHEMBL28433898 | 0.72 | SLC7A5 (0.65) | BLMNPSR1HTR1ANFKB1HTR2A | |
| Tyrosine SCHEMBL8316690 | 0.72 | SLC7A5 (0.65) | BLMNPSR1HTR1ANFKB1HTR2A | |
| Tyrosine SCHEMBL8315968 | 0.72 | SLC7A5 (0.65) | BLMNPSR1HTR1ANFKB1HTR2A | |
| Tyrosine SCHEMBL606713 | 0.72 | SLC7A5 (0.65) | BLMNPSR1HTR1ANFKB1HTR2A | |
| Tyrosine SCHEMBL606712 | 0.72 | SLC7A5 (0.65) | BLMNPSR1HTR1ANFKB1HTR2A | |
| Histidine SCHEMBL3050310 | 0.71 | SLC7A5 (0.49) | BLMNPSR1NFKB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227117-A1 | POLYMERIZATION CATALYSTS FOR POLYESTERS, POLYESTERS PRODUCED WITH THE SAME AND PROCESS FOR PRODUCTION OF POLYESTERS | Toyo Boseki Kabushiki Kaisha (JP) | 2002-07-31 | — | — | EP | disclosed |