Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7619298 | 0.98 | HIF1A (0.50) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL7613702 | 0.95 | KDM4E (0.48) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| Hydrochloric Acid SCHEMBL7612933 | 0.93 | KDM4E (0.47) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| Bromide SCHEMBL7613738 | 0.93 | KDM4E (0.47) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL7610185 | 0.87 | KDM4E (0.41) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| Hydrochloric Acid SCHEMBL3500893 | 0.85 | KDM4E (0.40) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| Bromide SCHEMBL7611201 | 0.85 | KDM4E (0.40) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| Bromide SCHEMBL7610282 | 0.84 | KDM4E (0.39) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL14598288 | 0.77 | KDM4E (0.65) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL26218458 | 0.75 | KDM4E (0.70) | HIF1AKDM4EMAPK1PAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888293-B1 | N-ACYLAMINOALKYLHYDRAZINECARBOXIMIDAMIDES | ALTEON INC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-5877217-A | INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. INHIBITING THE DISCOLORATION OF TEETH. | ALTEON INC. (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0888293-A1 | N-ACYLAMINOALKYLHYDRAZINECARBOXIMIDAMIDES | ALTEON, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997023447-A1 | N-ACYLAMINOALKYLHYDRAZINECARBOXIMIDAMIDES | ALTEON INC. (US) | 1997-07-03 | — | — | WO | disclosed |