Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620353 | 0.92 | NQO1 (0.43) | NQO1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7609210 | 0.89 | NQO1 (0.42) | NQO1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7610344 | 0.84 | MEN1 (0.56) | NQO1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7610904 | 0.83 | MAPT (0.40) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7617634 | 0.83 | MAPT (0.51) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7616823 | 0.81 | KMT2A (0.41) | KMT2AMAPTNPC1RAB9AGAA | |
| SCHEMBL7609256 | 0.80 | KMT2A (0.46) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7610155 | 0.76 | MEN1 (0.56) | NQO1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9208422 | 0.74 | MEN1 (0.46) | NQO1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7612240 | 0.74 | KMT2A (0.46) | NQO1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869785-B1 | 4-HYDROXYCOUMARIN-3-CARBOXAMIDES FOR THE TREATMENT OF NON-INSULIN DEPENDENT DIABETES MELLITUS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | claimed |