Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12534115 | 0.83 | HSP90AA1 (0.58) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL30611551 | 0.82 | PARP10 (0.47) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL3458382 | 0.82 | ALDH1A1 (0.53) | CA1CA2HSP90AA1PDK1PDK2 | |
| SCHEMBL3470955 | 0.82 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL2537515 | 0.82 | ALDH1A1 (0.71) | CA1CA2HSP90AA1PDK1PDK2 | |
| SCHEMBL31034446 | 0.80 | ALDH1A1 (0.44) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL22501255 | 0.80 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL7823913 | 0.80 | ALDH1A1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL11854125 | 0.80 | ALDH1A1 (0.51) | CA1CA2PARP10PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL11854130 | 0.80 | ALDH1A1 (0.51) | CA1CA2HSP90AA1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244631-A1 | NEW AZABICYCLOOCTANE DERIVATIVES USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-10-02 | — | — | EP | disclosed |
| US-6407220-B1 | FOR DYEING AND PRINTING OF MATERIALS CONTAINING CELLULOSE FIBERS; HIGH FIXATION AND GOOD BUILD-UP | EVERLIGHT USA, INC. | 2002-06-18 | — | — | US | disclosed |
| WO-2001047893-A1 | NEW AZABICYCLOOCTANE DERIVATIVES USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-07-05 | — | — | WO | disclosed |