Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115296 | 0.93 | TNF (0.40) | — | |
| SCHEMBL5120277 | 0.91 | RAB9A (0.36) | PDE5A | |
| SCHEMBL5123316 | 0.88 | BCDIN3D (0.42) | PDE5ABCDIN3D | |
| SCHEMBL5128407 | 0.88 | BCDIN3D (0.42) | PDE5ABCDIN3D | |
| SCHEMBL5125266 | 0.85 | PDE5A (0.48) | PDE5ABCDIN3D | |
| SCHEMBL5114702 | 0.85 | BCDIN3D (0.41) | PDE5ABCDIN3D | |
| SCHEMBL5122244 | 0.85 | PDE5A (0.46) | PDE5ABCDIN3D | |
| SCHEMBL5128625 | 0.84 | PDE5A (0.44) | PDE5A | |
| SCHEMBL5128720 | 0.84 | HTT (0.38) | PDE5A | |
| SCHEMBL5124878 | 0.84 | PDE5A (0.45) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432950-B1 | ANTICANCER AGENTS; KILLING CANCER CELLS | CELL PATHWAYS | 2002-08-13 | — | — | US | disclosed |
| US-6133271-A | Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives | CELL PATHWAYS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| US-6110920-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND IMPOTENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-08-29 | — | — | US | disclosed |