Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.66 |
| ▸ | DRD4 | P21917 | 12/20 | 0.66 |
| ▸ | DRD3 | P35462 | 9/20 | 0.66 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 2/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895109 | 0.98 | DRD2 (0.63) | DRD2DRD4DRD3KCNA3HTR1B | |
| SCHEMBL22144524 | 0.94 | DRD4 (0.74) | DRD2DRD4DRD3KCNA3HTR1B | |
| SCHEMBL2255625 | 0.88 | DRD4 (0.70) | DRD2DRD4DRD3HTR1BHTR1D | |
| SCHEMBL11895289 | 0.88 | DRD2 (0.83) | DRD2DRD4DRD3KCNA3HTR1B | |
| SCHEMBL8825989 | 0.87 | DRD2 (0.69) | DRD2DRD4DRD3KCNA3HTR1B | |
| Hydrochloric Acid SCHEMBL21879612 | 0.86 | DRD4 (0.68) | DRD2DRD4DRD3HTR1BHTR1D | |
| Bromide SCHEMBL21700365 | 0.86 | DRD4 (0.68) | DRD2DRD4DRD3HTR1BHTR1D | |
| SCHEMBL11894925 | 0.86 | DRD2 (0.80) | DRD2DRD4DRD3KCNA3HTR1B | |
| SCHEMBL11895180 | 0.85 | DRD2 (0.67) | DRD2DRD4DRD3KCNA3HTR1B | |
| Naphthalene SCHEMBL11676095 | 0.83 | DRD4 (0.63) | DRD2DRD4DRD3HTR1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437147-B1 | FOR THERAPY OF DISEASES OF CENTRAL NERVOUS SYSTEM, PERIPHERAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGICAL SYSTEM | NOVO NORDISK (DK) | 2002-08-20 | — | — | US | disclosed |