Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Alanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.33 |
| ▸ | GABRE | P78334 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL1436676 | 0.93 | — | — | |
| Alanine SCHEMBL10814860 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL5943276 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL19326825 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL497114 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL7614895 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL735033 | 0.93 | — | — | |
| Alanine SCHEMBL7532124 | 0.93 | CA1 (0.44) | SLC7A5CA1CA2CYP3A4TSHR | |
| Alanine SCHEMBL4669777 | 0.93 | — | — | |
| Alanine SCHEMBL15111230 | 0.93 | SLC7A5 (0.38) | SLC7A5CA1CA2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927232-B1 | ELECTRODEPOSITABLE COATING COMPOSITION CONTAINING BISMUTH AND AMINO ACID MATERIALS AND ELECTRODEPOSITION METHOD | PPG IND OHIO INC (US) | 2002-01-16 | — | — | EP | disclosed |